Rockets vs. Cavaliers odds, prediction: 2025 NBA picks for Wednesday, November 19 from proven model

Title contenders meet during the Wednesday NBA schedule as the Houston Rockets travel to take on the Cleveland Cavaliers. Kevin Durant and the Rockets are off to a 9-3 start, while the Cavs are 10-5. It’s been a different story against the spread, however, as Houston is 8-4 ATS and Cleveland is just 5-10. Jabari Smith (knee) is questionable for the Rockets, while Darius Garland (toe) remains out for Cleveland.

Tipoff is set for 7 p.m. ET in Cleveland. Houston is a 1.5-point road favorite in the latest Rockets vs. Cavaliers odds, while the over/under is 233.5. Before making any Cavaliers vs. Rockets picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 5 of the 2025-26 NBA season on a sizzling 28-13 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated Rockets vs. Cavaliers 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Cavs vs. Rockets:

How to make Rockets vs. Cavaliers picks

SportsLine’s model has simulated Rockets vs. Cavaliers 10,000 times and is going Over 233.5 combined points. The trends clearly point in this direction with six straight Houston games going Over, while six of the past eight games for Cleveland have cleared the total. 

The model projects 237 combined points as the Over clears in well over 50% of simulations.

The model also says one side of the spread hits well over 60% of the time. You can head to SportsLine to see the model’s NBA picks. 

So who wins Rockets vs. Cavs, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.